Clayton-Wolfindale graduated from Liverpool Hope University in 2006 with a degree in Fine Art and Education Studies. After two years as a health care assistant she began work at TATE Britain/Modern in 2009 and later at the National Gallery, London in 2012. She also spent three and a half years working at a substance misuse detox residential unit during 2012 -2015 as an Activity and Volunteer Co-ordinator. Her interests lie in using art to bring about wellbeing. She is particularly interested in how the subconscious mind reveals itself through the creative process. Clayton-Wolfindale uses a variety of different media including paint, film, animation, installation, and performance.